Therapeutic angiogenesis and vasculogenesis for tissue regeneration

Angiogenesis and vasculogenesis for therapeutic neovascularization.

Peripheral blood of adult species contains endothelial progenitor cells (EPCs) that participate in neovascularization, consistent with postnatal vasculogenesis. EPCs can be isolated not only from peripheral blood but also from bone marrow and human umbilical cord blood. In vitro culture-expanded EPCs participate in endothelial network formation (capillary formation) in vitro, and transplanted E...

Angiogenesis and vasculogenesis as therapeutic strategies for postnatal neovascularization.

The role of therapeutic angiogenesis in tissue repair and regeneration.

PURPOSE To provide the physician and registered professional nurse with an understanding of angiogenesis and an overview of therapeutic angiogenesis modalities used to manage wounds and other tissue repair situations. TARGET AUDIENCE This continuing education activity is intended for physicians and nurses with an interest in learning more about angiogenesis and therapeutic angiogenesis modali...

Principles and therapeutic implications of angiogenesis, vasculogenesis and arteriogenesis.

The vasculature is the first organ to arise during development. Blood vessels run through virtually every organ in the body (except the avascular cornea and the cartilage), assuring metabolic homeostasis by supplying oxygen and nutrients and removing waste products. Not surprisingly therefore, vessels are critical for organ growth in the embryo and for repair of wounded tissue in the adult. Not...

Therapeutic angiogenesis and vasculogenesis for ischemic disease: part II: cell-based therapies.

Cell Therapy For Therapeutic Vascularization Endothelial Progenitor Cells and Postnatal Vasculogenesis: Experimental Evidence The option of performing full-scale endothelial cell transplantation to optimize local neovascularization is daunting if even feasible. An alternative, attractive strategy is designed to exploit the conceptual notion that endothelial cells and hematopoietic stem cells we...